Thanks for the advice.
I suppose it is best to roll up my sleeves and compete on some of these lines instead of opening that second base airport. The lines I'll be competing on are already oversupplied by competition. Upon closer inspection of my competitors, I'm starting to think a better name for this game world is Seal Clubber World #1.
These are the routes I'm considering opening right now instead of going for new base:
Route 1:
1) Its not my Avros (can hardly find them at all anymore) vs 737s. It will be my ATRs vs 10 E140/E145 flights and 2 A318 flights.
2) The airline i'm competing with makes $ 87.5 in profit per quarter. 30th ranked airline in world. User account register this year--an actual beginner.
3) Avg dem 960. Supply 768.
Route 2:
1) 2 competitors running a combined 7 flights.
2) Competitor 1 is ranked #2 in world with quarterly profits that float near $1 billion. User account is 11 months old (irl time).
3) Competitor 2 isn't much smaller than 1. #7 in world. User account 5 years old (irl time). Hmmm. Still beginner?
4) 2 x A321 flights.
5) 5 x SU95 flights.
6) avg dem 860. supply 839.
Route 3:
1) 1 competitor running a single A321.
2) Dem 260. Supply 185.

3) Competitor has $1 mil profit last quarter. Ranked #3 in world. User account registered in April.
4) This route is a bit on the long side for my ATR fleet at 525nm.
I plan to use the ATR for all new routes for the time being. I'm slowly phasing out Avro as they are too rare. My company image is at 32.
Please feel free to share thoughts and insights about the routes I've listed above.