This should be made available in games. Airbus has already announced the project!
https://www.airbus.com/newsroom/news/en/2020/02/a-new-life-for-a321s-as-highly-efficient-freighter-aircraft.html
I don't see anything in the linked article to suggest it's based on the 321neo?
The 321-200F conversion is already in-game.
I could not find a single mention of A321Neo in the link you provided.
The regular A321 can already be converted to freighter in the game.