You've got 5 different fleets, but just 15 planes. That means you're paying a lot of extra maintenance.
Most of your jumbo flights are departing or arriving in the middle of the night.
You haven't paid enough attention to how far your plane can fly, or possibly how much runway it needs. Your jumbo flight to Bangkok only has 73 seats available due to range or runway, even though it's a 347 seat plane. So I'm sure that flight is losing money.
Some of your flights (to Catania, Bologna, Napoli, Amsterdam) are probably too close together, meaning they get penalised.
You are using very short turnaround times (I see 50 minutes for 737, 140 minutes for 744, 60 minutes for 722), meaning high numbers of delays & cancellations.
Your flights in general are pretty erratic, flying 1-4 times a week to many different places. Much better if you can fly once/day, and makes it easier to schedule too. I know Milan is very slot restricted, which makes that tough.
I suspect your marketing budget is on the large side, how much do you spend per week on that, and how much is your revenue? Marketing being 10% of revenue should be more than enough at this stage.
Looking at your routes, I don't see many that have a huge amount of comp. So it's a little surprising that your overall LF is so low. I suspect if you took the jumbos out, the LF would climb back up above 60%.
So, you're pretty inefficient in general, which means less revenue and higher maintenance costs. Add in the jumbos, which I assume are all losing money thanks to high lease prices and middle of the night flights, and that has your airline losing money overall.